2-Hexyl-4-Pentynoic Acid

CAT:

26-B2834-500

Size:

500 mg

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Description: 2-Hexyl-4-Pentynoic Acid is an inhibitor of histone deacetylases (HDACs). It is a derivative of Valproic acid. It inhibits HDAC activity with an IC₅₀ of 13 μM, compared to an IC₅₀ of 398 μM for Valproic acid. It induces histone hyperacetylation at a concentration of 5 μM in cerebellar granule cells and increases HSP70-1a and HSP70-1b mRNA levels at 50 μM. It is neuroprotective against glutamate-induced excitotoxicity.
Shipping Conditions: RT
Storage Conditions: -20ºC
Shelf Life: 24months

Cat	Name
B2834-100	2-Hexyl-4-Pentynoic Acid
B2834-500	2-Hexyl-4-Pentynoic Acid
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