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JFD00244

CAT: 0026-B2830-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-B2830-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JFD00244 is an inhibitor of SIRT2. SIRT2 is a NAD+ (nicotinamide adenine dinucleotide)-dependent deacetylase. A major substrate of SIRT2 is α-tubulin. JFD00244 inhibits SIRT2 with an IC₅₀ of 56.7 µM. It induces granulocytic differentiation in the acute promyelocytic leukemia cell line NB4 at a concentration of 5 μM.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months

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