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Tenovin-6

CAT: 0026-B2818-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2818-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tenovin-6 is a SirT2 inhibitor and a p53 activator. It is a water-soluble analog of Tenovin-1. Tenovins inhibit the protein-deacetylase activities of SirT1 and SirT2. The IC₅₀ for inhibiting human SirT1 and SirT2 peptide deacetylase activity is 21 μM and 10 μM respectively. Tenovin-6 potently inhibits the proliferation of diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia cells.
Shipping Conditions
RT
Storage Conditions
-20ºC
Shelf Life
36 months