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Wedelolactone

CAT: 0026-B2811-1Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0026-B2811-1Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Wedelolactone is a natural coumestan that irreversibly inhibits IKK in NF-κB signaling pathway. IKK phosphorylates the IκBα protein, which results in the degradation and dissociation of IκBα from NF-κB leading to NF-κB activation. Wedelolactone has anti-inflammatory effect through inhibiting IKK activity and caspase-11 expression. It improves lipid metabolism partly by AMPK activation and up-regulation of expression of PPARα/Lipopoptein Lipase and Low Density Lipoprotein Receptor.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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CatalogName
301116Wedelolactone

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