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Cysmethynil

CAT: 0026-B2544-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0026-B2544-5Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Cysmethynil is a potent, time-dependent inhibitor of Icmt (IC₅₀= <200 nM). It acts as a competitive inhibitor with respect to the isoprenylated cysteine substrate and a noncompetitive inhibitor with respect to S-adenosylmethionine (Ki = 0.14 µM for the final complex). It does not inhibit other enzymes in the prenylation pathway (farensyltransferase, geranylgeranyltransferase type I, and Rce1) at concentrations up to 50 µM, or related methyltransferases.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months