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CBR-5884

CAT: 0026-B2543-25Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0026-B2543-25Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CBR-5884 is a potent and selective inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) (IC₅₀ = 33 μM) inhibiting serine synthesis from 3-phosphoglycerate in cells. CBR-5884 inhibits serine biosynthesis in cells with no effect on two other dehydrogenases, lactate dehydrogenase and MDH1 and without general cytotoxic effects up to 40 μM. CBR-5884 is selectively toxic to tumor cells with high serine synthesis activity.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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