CEP-37440

CAT: 0026-B2504-1Size: 1 mgDry Ice: NoHazardous: No
CAT#:0026-B2504-1Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CEP-37440 is a potent and selective dual FAK/ALK inhibitor with IC₅₀ s of 2.3 nM (FAK) and 120 nM (ALK cellular IC₅₀ in 75% human plasma). The inhibition leads to disruption of ALK- and FAK-mediated signal transduction pathways and eventually inhibits tumor cell growth in ALK- and FAK-overexpressing tumor cells. It blocks the proliferation of inflammatory and triple-negative breast cancer cell lines but not normal breast epithelial cells.
Shipping Conditions
Gel Pack
Storage Conditions
-20ºC
Shelf Life
36 months

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