M-PEG5-Propyne

• Description:

  M-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• UNSPSC:

  12352211

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  PROTAC Linkers

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/m-peg5-propyne.html

• Purity:

  95.95

• Solubility:

  10 mM in DMSO

• Smiles:

  COCCOCCOCCOCCOCCOCC#C

• Molecular Formula:

  C14H26O6

• Molecular Weight:

  290.35

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-1006.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, stored under nitrogen, away from moisture)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  [1101668-41-0]