M-PEG5-Propyne

• Description :

  M-PEG5-Propyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. m-PEG5-Propyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

• CAS Number :

  [1101668-41-0]

• UNSPSC :

  12352211

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  PROTAC Linkers

• Type :

  Reference compound

• Related Pathways :

  PROTAC

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/m-peg5-propyne.html

• Purity :

  95.95

• Solubility :

  10 mM in DMSO

• Smiles :

  COCCOCCOCCOCCOCCOCC#C

• Molecular Formula :

  C14H26O6

• Molecular Weight :

  290.35

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27 (8) :998-1006.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, stored under nitrogen, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers