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VUF14738

CAT: 0804-HY-126749Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-126749Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
VUF14738 (compound 28) is a bidirectional photoswitch antagonist that can rapidly and reversibly photoisomerize at the histamine H3 receptor, with binding affinity increased or decreased upon illumination, and can be used in real-time electrophysiological experiments to study the activity of dynamic light modulation of receptor activation.
CAS Number
2223027-70-9
UNSPSC
12352005
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/vuf14738.html
Smiles
O=C(C1=CC=CC(/N=N/C2=CC=CC(OCCCN3CCCCC3)=C2)=C1)N4CCCC4
Molecular Formula
C25H32N4O2
Molecular Weight
420.55
References & Citations
[1]Synthesis and Characterization of a Bidirectional Photoswitchable Antagonist Toolbox for Real-Time GPCR Photopharmacology
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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