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Deracoxib (Standard)

CAT: 0804-HY-17509R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-17509R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Deracoxib (SC 046; SC 59046) (Standard) is the analytical standard of Deracoxib. This product is intended for research and analytical applications. Deracoxib, an orally active COX-2 inhibitor, is a veterinary nonsteroidal anti-inflammatory agent used exclusively in dogs. Deracoxib inhibits the COX-2 enzyme to reduce the production of prostaglandins, effectively controlling pain and inflammation after canine soft tissue surgery. Deracoxib reduces the inhibition of COX-1 and lowers the risk of gastrointestinal side effects. Deracoxib induces tumor cell cycle arrest and apoptosis, and shows anti-tumor activity in canine osteosarcoma, breast tumors and bladder transitional cell carcinomas
CAS Number
169590-41-4
Product Name Alternative
SC 046 (Standard) ; SC 46 (Standard) ; SC 59046 (Standard)
UNSPSC
12352005
Target
Apoptosis; COX; Reference Standards
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Others
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/deracoxib-standard.html
Smiles
O=S(C1=CC=C(N2N=C(C(F)F)C=C2C3=CC=C(OC)C(F)=C3)C=C1)(N)=O
Molecular Formula
C17H14F3N3O3S
Molecular Weight
397.37
References & Citations
[1]Royals, S.R., et al., Investigation of the effects of deracoxib and piroxicam on the in vitro viability of osteosarcoma cells from dogs. Am J Vet Res, 2005. 66 (11) : p. 1961-7.|[2]Ustun Alkan, F., et al., The effects of piroxicam and deracoxib on canine mammary tumour cell line. ScientificWorldJournal, 2012. 2012: p. 976740.|[3]Bienhoff, S.E., et al., Efficacy and safety of deracoxib for control of postoperative pain and inflammation associated with soft tissue surgery in dogs. Vet Surg, 2012. 41 (3) : p. 336-44.|[4]McMillan, S.K., et al., Antitumor effects of deracoxib treatment in 26 dogs with transitional cell carcinoma of the urinary bladder. J Am Vet Med Assoc, 2011. 239 (8) : p. 1084-9.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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