Ecamsule

• Description:

  Ecamsule is a broad-spectrum UVA filter that can be used in sunscreen product. Ecamsule reduces biological damage caused by solar radiation such as pyrimidine dimer formation, p53 protein accumula-tion, or collagenase 2 expression. Ecamsule has the potential for the research of polymorphous light eruption (PMLE) [1] [2].

• UNSPSC:

  12352005

• Hazard Statement:

  H318

• Target:

  Biochemical Assay Reagents

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/ecamsule.html

• Purity:

  98.02

• Solubility:

  Ethanol : 50 mg/mL (ultrasonic) |Methanol : 31.25 mg/mL (ultrasonic)

• Smiles:

  O=[S](CC(C1=O)(CCC2/C1=C/C(C=C3)=CC=C3/C=C(C4=O)/C(CCC45C[S](=O)(O)=O)C5(C)C)C2(C)C)(O)=O

• Molecular Formula:

  C28H34O8S2

• Molecular Weight:

  562.69

• Precautions:

  H318

• References & Citations:

  [1]Stefanie Hofer, et al. Contradictory effects of chemical filters in UV/ROS-stressed human keratinocyte and fibroblast cells. ALTEX. 2019;36 (2) :231-244.|[2]DeLeo VA, et al. A new ecamsule-containing SPF 40 sunscreen cream for the prevention of polymorphous light eruption: a double-blind, randomized, controlled study in maximized outdoor conditions. Cutis. 2009 Feb;83 (2) :95-103.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [92761-26-7]