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Betazole

CAT: 0804-HY-B1557-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1557-01Size:5 mg
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Description
Betazole (Ametazole), a pyrazole analogue of histamine, is an orally active histamine H2 receptor agonist. Betazole induces gastric acid secretion and causes an immediate and significant increase in common bile duct pressure. Betazole is used as a diagnostic agent known as histalog for investigating gastric acid secretory capacity[1][2][3].
CAS Number
105-20-4
Product Name Alternative
Ametazole
UNSPSC
12352005
Hazard Statement
H315, H319, H320
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/betazole.html
Purity
96.66
Solubility
DMSO : 175 mg/mL (ultrasonic) |H2O : 35 mg/mL (ultrasonic)
Smiles
NCCC1=NNC=C1
Molecular Formula
C5H9N3
Molecular Weight
111.15
Precautions
H315, H319, H320
References & Citations
[1]Maples MD, Effects of betazole hydrochloride and cimetidine on common bile pressure and duodenal myoelectric activity in the dog. Am Surg. 1981;47 (12) :519-521.|[2]Spitz IM, Betazole-induced GIP secretion is not mediated by gastric HCl. Metabolism. 1982;31 (4) :380-382.|[3]CLAYMAN CB, . A simple oral gastric secretory stimulant (betazole hydrochloride) . JAMA. 1961;175:908-909.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
H2 Receptor

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