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HIV gp120 (421-438)

CAT: 0804-HY-P10252Size: 1 EachDry Ice: NoHazardous: No
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Description
HIV gp120 421-438 is HIV antigen fragments, that conjugates with keyhole limpet hemocyanin (KLH) and generates specific anti-HIV antibody[1].
CAS Number
129318-38-3
UNSPSC
12352209
Target
HIV
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hiv-gp120-421-438.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](C)C(N2[C@@H](CCC2)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)NC([C@H](CCSC)NC([C@H](C)NC([C@H](CCCCN)NC(CNC([C@H](C(C)C)NC([C@H](CCC(O)=O)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCSC)NC([C@H](CC(N)=O)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@@H](N)CCCCN)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C99H148N24O25S2
Molecular Weight
2138.51
References & Citations
[1]Justiz-Vaillant A, et al., In vivo administration of anti-HIV hyper-immune eggs induces anti-anti-idiotypic antibodies against HIV gp120 peptides (fragments 308-331 and 421-438) and against HIV gp41 peptide (fragment 579-601) which have demonstrable protective capacity[J]. bioRxiv, 2021: 2021.05. 02.442298.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported

Chemical Information

HIV gp120 (421-438)
CAS Number129318-38-3
PubChem CID71312139
IUPAC Name(2S)-1-[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-5-amino-2-[[(2S)-2,6-diaminohexanoyl]amino]-5-oxopentanoyl]amino]-3-phenylpropanoyl]amino]-3-methylpentanoyl]amino]-4-oxobutanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-oxopentanoyl]amino]-4-carboxybutanoyl]amino]-3-methylbutanoyl]amino]acetyl]amino]hexanoyl]amino]propanoyl]amino]-4-methylsulfanylbutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]pyrrolidine-2-carboxylic acid
Molecular FormulaC99H148N24O25S2
Molecular Weight2138.5
XLogP-6.1
Topological Polar Surface Area846
Hydrogen Bond Donor Count25
Hydrogen Bond Acceptor Count30
Rotatable Bond Count67
Heavy Atom Count150
Formal Charge0
Complexity4550
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC3=CC=C(C=C3)O)C(=O)N[C@@H](C)C(=O)N4CCC[C@H]4C(=O)N5CCC[C@H]5C(=O)O)NC(=O)[C@H](CC6=CC=CC=C6)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCCCN)N
InChI
InChI=1S/C99H148N24O25S2/c1-9-54(4)82(121-94(142)71(47-57-21-11-10-12-22-57)117-87(135)65(33-36-76(103)125)112-84(132)62(102)24-15-17-41-100)96(144)119-73(50-78(105)127)93(141)115-69(40-46-150-8)89(137)118-72(49-59-51-106-63-25-14-13-23-61(59)63)92(140)114-66(34-37-77(104)126)86(134)113-67(35-38-80(129)130)90(138)120-81(53(2)3)95(143)107-52-79(128)110-64(26-16-18-42-101)85(133)108-55(5)83(131)111-68(39-45-149-7)88(136)116-70(48-58-29-31-60(124)32-30-58)91(139)109-56(6)97(145)122-43-19-27-74(122)98(146)123-44-20-28-75(123)99(147)148/h10-14,21-23,25,29-32,51,53-56,62,64-75,81-82,106,124H,9,15-20,24,26-28,33-50,52,100-102H2,1-8H3,(H2,103,125)(H2,104,126)(H2,105,127)(H,107,143)(H,108,133)(H,109,139)(H,110,128)(H,111,131)(H,112,132)(H,113,134)(H,114,140)(H,115,141)(H,116,136)(H,117,135)(H,118,137)(H,119,144)(H,120,138)(H,121,142)(H,129,130)(H,147,148)/t54-,55-,56-,62-,64-,65-,66-,67-,68-,69-,70-,71-,72-,73-,74-,75-,81-,82-/m0/s1
InChIKey
FWLUYNSJWIJPKZ-WEARTWMDSA-N
Chemical Structure
2D Structure
2D structure of HIV gp120 (421-438)
CAS: 129318-38-3
CID: 71312139
Formula: C99H148N24O25S2
MW: 2138.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight2138.5
XLogP3-6.1
Hydrogen Bond Donor Count25
Hydrogen Bond Acceptor Count30
Rotatable Bond Count67
Exact Mass2138.0522435
Monoisotopic Mass2137.0488887
Topological Polar Surface Area846 Ų
Heavy Atom Count150
Formal Charge0
Complexity4550
Isotope Atom Count0
Defined Atom Stereocenter Count18
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
H-1354.1000HIV (gp120) Fragment (421-438)
CCP2470-01HIV-gp120-Fragment (421-438)
5-01330HIV -gp120- Fragment (421-438)
PE-89135-01HIV-gp120-Fragment (421-438) Peptide
FH108419-01HIV (gp120) Fragment (421-438) trifluoroacetate salt
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A2308-50TAK-438
WLB60587-01MF-438
T71037-01BAY-438
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