Cefazedone

• Description :

  Cefazedone (Refosporen) is a first-generation cephalosporin antibiotic. Cefazedone is active against both Gram-positive and Gram-negative bacteria[1][2].

• Product Name Alternative :

  Refosporen

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Antibiotic; Bacterial

• Type :

  Natural Products

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/cefazedone.html

• Purity :

  99.89

• Solubility :

  DMSO : 116.67 mg/mL (ultrasonic)

• Smiles :

  O=C(O)C(N1[C@@]([H])([C@@H](C1=O)NC(CN(C=C(C2=O)Cl)C=C2Cl)=O)SC3)=C3CSC4=NN=C(S4)C

• Molecular Formula :

  C18H15Cl2N5O5S3

• Molecular Weight :

  548.44

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Gao L, et al. A Pharmacokinetic and Pharmacodynamic Study on Intravenous Cefazedone Sodium in Patients with Community-acquired Pneumonia. Chin Med J (Engl) . 2015 May 5;128 (9) :1160-4.|[2]Bloom JC, et al. Cephalosporin-induced immune cytopenia in the dog: demonstration of erythrocyte-, neutrophil-, and platelet-associated IgG following treatment with cefazedone. Am J Hematol. 1988 Jun;28 (2) :71-8.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• CAS Number :

  [56187-47-4]