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For-Met-OH

CAT: 0804-HY-W016647-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W016647-01Size:100 mg
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Description
For-Met-OH (N-Formylmethionine) can be involved in the translation process of bacteria, chloroplasts, and mitochondria. For-Met-OH plays different roles in different species and organelles, such as promoting the formation of protein complexes in mitochondria and acting as a degradation signal in bacteria and yeast. The level of For-Met-OH is closely related to certain diseases, for example, For-Met-OH is a potential biomarker for metabolic disorders and poor prognosis in critically ill patients[1][2][3].
CAS Number
4289-98-9
Product Name Alternative
N-Formylmethionine
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Bacterial; Endogenous Metabolite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/for-met-oh.html
Purity
99.92
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
CSCC[C@@H](C(O)=O)NC=O
Molecular Formula
C6H11NO3S
Molecular Weight
177.22
Precautions
H302, H315, H319, H335
References & Citations
[1]Lee CS, et al. Where Does N-Formylmethionine Come from? What for? Where Is It Going? What is the origin of N-formylmethionine in eukaryotic cells? Mol Cells. 2022 Mar 31;45 (3) :109-111.|[2]Sigurdsson MI, et al. Circulating N-formylmethionine and metabolic shift in critical illness: a multicohort metabolomics study. Crit Care. 2022 Oct 19;26 (1) :321.|[3]Feng Y, et al. The major role of Listeria monocytogenes folic acid metabolism during infection is the generation of N-formylmethionine. mBio. 2023 Oct 31;14 (5) :e0107423.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite; Microbial Metabolite

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