Products for Research Use Only
RegisterLogin

Apricoxib

CAT: 0804-HY-14783-01Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14783-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Apricoxib (CS 706) is a selective inhibitor for cyclooxygenase-2 (COX-2) . Apricoxib inhibits the production of PGE2 in cells with IC50 of 1.5 nM. Apricoxib exhibits anticancer, analgesic and anti-inflammatory activities[1].
CAS Number
197904-84-0
Product Name Alternative
CS 706; R 109339; TG 01
UNSPSC
12352005
Target
COX; Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/apricoxib.html
Smiles
O=S(C1=CC=C(N2C(C3=CC=C(OCC)C=C3)=CC(C)=C2)C=C1)(N)=O
Molecular Formula
C19H20N2O3S
Molecular Weight
356.44
References & Citations
[1]Reckamp K, et al., Biomarker-based phase I dose-escalation, pharmacokinetic, and pharmacodynamic study of oral apricoxib in combination with erlotinib in advanced nonsmall cell lung cancer. Cancer. 2011 Feb 15;117 (4) :809-18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

Alternative Products

CatalogName
162666Apricoxib
sc-480139Apricoxib-d4

Popular Products