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3α-Dihydrocadambine

CAT: 0804-HY-N4209-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N4209-01Size:1 mg
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Description
3α-Dihydrocadambine is a natural product isolated from the heartwoods of Anthocephalus cadamba.3α-Dihydrocadambine exhibits dose-dependent hypotensive and anti-hypertensive effects in anesthetized normotensive rats and in conscious spontaneously hypertensive rats[1][2].
CAS Number
54483-84-0
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/3α-dihydrocadambine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1CN2[C@](C[C@@](C(C(OC)=O)=CO3)([H])[C@]1([H])[C@@H]3O[C@@H]([C@@H]([C@H]4O)O)O[C@@H]([C@H]4O)CO)([H])C5=C(CC2)C6=CC=CC=C6N5
Molecular Formula
C27H34N2O10
Molecular Weight
546.57
References & Citations
[1]Takayama H, et al. Gluco-indole alkaloids from Nauclea cadamba in Thailand and transformation of 3 alpha-dihydrocadambine into the indolopyridine alkaloid, 16-carbomethoxynaufoline. Chem Pharm Bull (Tokyo) . 2003;51 (2) :232-233.|[2]K Aisaka, et al. Hypotensive action of 3 alpha-dihydrocadambine, an indole alkaloid glycoside of Uncaria hooks. Planta Med. 1985 Oct;51 (5) :424-7.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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