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IMTPPE

CAT: 0804-HY-121588Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121588Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IMTPPE is an inhibitor of the androgen receptor (AR) in C4-2 prostate cancer cells, inhibiting its transcriptional activity and protein levels. IMTPPE inhibited the proliferation of AR-positive prostate cancer cells but had no effect on AR-negative prostate cancer cells. IMTPPE also inhibited the growth of enzalutamide-resistant 22Rv1 xenograft tumors[1].
CAS Number
851688-13-6
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/imtppe.html
Smiles
O=C(CSCC1=C(ON=C1C)C)N2CCN(CC2)C3=CC=CC(C)=C3C
Molecular Formula
C20H27N3O2S
Molecular Weight
373.51
References & Citations
[1]Inhibition of androgen receptor function and level in castration-resistant prostate cancer cells by 2- ((isoxazol-4-ylmethyl) thio) -1- (4-phenylpiperazin-1- yl) ethanone
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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