Products for Research Use Only
RegisterLogin

Fluorometholone acetate

CAT: 0804-HY-B1471-01Size: 25 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-B1471-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Fluorometholone acetate is a synthetic glucocorticoid corticosteroid and a corticosteroid ester. Fluorometholone acetate potently inhibits carbonic anhydrase (CA) with IC50s of 2.18 μM and 17.5 μM for hCA-I and hCA-II, respectively. Fluorometholone acetate has anti-inflammatory effect and has the potential for external ocular inflammation research[1][2][3].
CAS Number
3801-06-7
UNSPSC
12352211
Hazard Statement
H360
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/fluorometholone-acetate.html
Concentration
10mM
Purity
98.54
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC([C@@]1(OC(C)=O)CC[C@@]2([H])[C@]3([H])C[C@H](C)C4=CC(C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)=O)=O
Molecular Formula
C24H31FO5
Molecular Weight
418.50
Precautions
H360
References & Citations
[1]A Kupferman, et al. Fluorometholone acetate. A new ophthalmic derivative of fluorometholone. Arch Ophthalmol. 1982 Apr;100 (4) :640-1.|[2]Zuhal Alım, et al. Some Anti-Inflammatory Agents Inhibit Esterase Activities of Human Carbonic Anhydrase Isoforms I and II: An In Vitro Study. Chem Biol Drug Des. 2015 Oct;86 (4) :857-63.|[3]H M Leibowitz, et al. Fluoro metholone acetate: clinical evaluation in the treatment of external ocular inflammation. Ann Ophthalmol. 1984 Dec;16 (12) :1110-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
CA II

Related Products

CatalogName
HY-B1893-01Fluorometholone
HY-B1893R-01Fluorometholone (Standard)
HY-166875SApramycin acetate-d7 (acetate)
HY-134716Methyl acetate-PEG1-methyl acetate
HY-W127616-01β-Sitosterol acetate, 40% (contains Campesterol acetate)
HY-P4091A-01LSD (acetate)
HY-P2483B-01Octaarginine (acetate)
HY-P10959A-01Macupatide (acetate)
HY-P10517A-01Sifuvirtide (acetate)
HY-P0013A-01Antide (acetate)

Alternative Products

CatalogName
FF23441-01Fluorometholone acetate
276366-01Δ-9 (11) -Fluorometholone acetate
FE22754-01(9b,11b) -Epoxy fluorometholone acetate
TRC-E589215-10MG(9Beta,11Beta)-Epoxy Fluorometholone Acetate
TRC-F593165-250MGdelta-9(11)-Fluorometholone Acetate
sc-497494(9β,11β) -Epoxy Fluorometholone Acetate

Popular Products