GNE-477

• Description:

  dual PI3K/mTOR inhibitor

• Product Name Alternative:

  5-(7-methyl-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)-4-morpholinothieno[3,2-d]pyrimidin-2-yl)pyrimidin-2-amine

• Field of Research:

  PI3K Akt mTOR Signaling mTOR

• Purity:

  0.9885

• Solubility:

  insoluble in H2O; insoluble in EtOH; ≥16.69 mg/mL in DMSO with gentle warming

• Smiles:

  O=S(N1CCN(CC2=C(C)C3=NC(C4=CN=C(N)N=C4)=NC(N5CCOCC5)=C3S2)CC1)(C)=O

• Molecular Formula:

  C21H28N8O3S2

• Molecular Weight:

  504.63

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Desiccate at -20°C.

• CAS Number:

  1032754-81-6