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Nepetoidin B

CAT: 0804-HY-N8263Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N8263Size:1 Each
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Description
Nepetoidin B, an anti-inflammatory agent, inhibits inflammation by modulating the NF-κB and Nrf2/HO-1 signaling pathways. Nepetoidin B also has antifungal and antibacterial activity. Nepetoidin B is a natural product that can be obtained from Salvia plebeia R. Br. Nepetoidin B can be used in anti-inflammatory and anti-infectious research[1][2].
CAS Number
55486-06-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Bacterial; Fungal; NF-κB
Type
Natural Products
Related Pathways
Anti-infection; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nepetoidin-b.html
Solubility
10 mM in DMSO
Smiles
O=C(O/C=C\C1=CC=C(O)C(O)=C1)/C=C/C2=CC=C(O)C(O)=C2
Molecular Formula
C17H14O6
Molecular Weight
314.29
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Kim M, et al. Nepetoidin B from Salvia plebeia R. Br. Inhibits Inflammation by Modulating the NF-κB and Nrf2/HO-1 Signaling Pathways in Macrophage Cells. Antioxidants (Basel) . 2021 Jul 28;10 (8) :1208. |[2]Wu X, et al. Nepetoidin B, a Natural Product, Inhibits LPS-stimulated Nitric Oxide Production via Modulation of iNOS Mediated by NF-κB/MKP-5 Pathways. Phytother Res. 2017 Jul;31 (7) :1072-1077.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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