LOXO-101

• Description:

  tropomyosin receptor kinases (TRK) inhibitor

• Product Name Alternative:

  (S)-N-(5-((R)-2-(2,5-difluorophenyl)pyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidin-3-yl)-3-hydroxypyrrolidine-1-carboxamide sulfate

• Sequence:

  Larotrectinib

• Field of Research:

  Tyrosine Kinase Trk

• Purity:

  0.9951

• Form:

  A solid

• Solubility:

  ≥18.47 mg/mL in DMSO; ≥2.14 mg/mL in EtOH; ≥29.65 mg/mL in H2O

• Smiles:

  O=S(O)(O)=O.O=C(N1C[C@@H](O)CC1)NC2=C3N=C(N4[C@@H](C5=CC(F)=CC=C5F)CCC4)C=CN3N=C2

• Molecular Formula:

  C21H24F2N6O6S

• Molecular Weight:

  526.51

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1223405-08-0