Dasatinib Monohydrate

• Description:

  Inhibitor of ABL, SRC, KIT, PDGFR, and other tyrosine kinases.

• Product Name Alternative:

  (Z)-N-(2-chloro-6-methylphenyl)-2-((6-(4-(2-hydroxyethyl)piperazin-1-yl)-2-methylpyrimidin-4-yl)amino)thiazole-5-carbimidic acid hydrate

• Field of Research:

  TGF-β Smad Signaling Bcr-Abl

• Purity:

  0.9976

• Form:

  A solid

• Solubility:

  ≥25.3 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

• Smiles:

  CC1=C(/N=C(O)/C(S2)=CN=C2NC3=CC(N4CCN(CCO)CC4)=NC(C)=N3)C(Cl)=CC=C1.O

• Molecular Formula:

  C22H28ClN7O3S

• Molecular Weight:

  506.02

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  863127-77-9