Dovitinib (TKI258) Lactate

• Description:

  Oral tyrosine kinase inhibitor (TKI) against FGFR1–3, VEGFR1–3, and platelet-derived growth factor receptor (PDGFR).

• Product Name Alternative:

  4-amino-5-fluoro-3-(6-(4-methylpiperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one 2-hydroxypropanoate hydra

• Field of Research:

  Tyrosine Kinase VEGFR

• Purity:

  0.9963

• Solubility:

  insoluble in EtOH; ≥10.62 mg/mL in DMSO; ≥168.2 mg/mL in H2O

• Smiles:

  FC1=C(C(N)=C(C2=O)C3=NC4=C(N3)C=C(N5CCN(C)CC5)C=C4)C(N2)=CC=C1.CC(O)C(O)=O.O

• Molecular Formula:

  C24H29FN6O5

• Molecular Weight:

  500.52

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  915769-50-5