Rolapitant HCl

• Description :

  Orally active neurokinin NK1 receptor antagonist.

• Product Name Alternative :

  (5S,8S)-8-(((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)methyl)-8-phenyl-1,7-diazaspiro[4.5]dec-1-en-2-ol hydrochloride

• Field of Research :

  GPCR G protein NK Receptor

• Purity :

  0.9913

• Solubility :

  insoluble in H2O; ≥28.7 mg/mL in EtOH with ultrasonic; ≥32.9 mg/mL in DMSO

• Smiles :

  C[C@]([H])(C1=CC(C(F)(F)F)=CC(C(F)(F)F)=C1)OC[C@]2(CC[C@]3(CCC(O)=N3)CN2)C4=CC=CC=C4.Cl

• Molecular Formula :

  C25H27ClF6N2O2

• Molecular Weight :

  536.94

• Shipping Conditions :

  Blue ice

• Storage Conditions :

  Store at -20°C.

• CAS Number :

  552292-08-7 (free base)