TED-347

CAT: 0026-B3247-5Size: 5 mgDry Ice: NoHazardous: No

CAT#:0026-B3247-5Size:5 mg

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Description

TED-347 is a potent, irreversible, covalent and allosteric inhibitor at YAP-TEAD protein-protein interaction with an EC50 of 5.9 μM for TEAD4⋅Yap1 protein-protein interaction. TED-347 specifically and covalently bonds with Cys-367 within the central pocket of TEAD4 with a Ki of 10.3 μM. TED-347 blocks TEAD transcriptional activity and displays antitumor activity.

Shipping Conditions

Gel Pack

Storage Conditions

-20ºC

Shelf Life

36 months

Related Products

Catalog	Name

Alternative Products

Catalog	Name
BUP04716-01	TED-347
MN 745120.5	Protino Ni-TED
E235-423-13	Magose Ni-TED

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