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Bifenazate

CAT: 0804-HY-119687-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119687-01Size:100 mg
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Description
Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm[1]. Bifenazate is a positive allosteric modulator of GABA receptor[2]. Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III[3].
CAS Number
149877-41-8
UNSPSC
12352005
Hazard Statement
H317
Target
GABA Receptor; Insecticide; Mitochondrial Metabolism; Na+/K+ ATPase; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB; Others
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/bifenazate.html
Concentration
10mM
Purity
99.89
Solubility
DMSO : ≥ 250 mg/mL
Smiles
COC1=CC=C(C2=CC=CC=C2)C=C1NNC(OC(C)C)=O
Molecular Formula
C17H20N2O3
Molecular Weight
300.35
Precautions
H317
References & Citations
[1]Dekeyser, M.A., McDonald, P.T., and Angle, G.W., Jr. The discovery of bifenazate, a novel carbazate acaricide Chimia 57 (11), 702-704 (2003) .|[2]Hiragaki S, et al. A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae]. Neurotoxicology. 2012 Jun;33 (3) :307-13.|[3]Ma J, et al., Bifenazate exposure induces cardiotoxicity in zebrafish embryos. Environ Pollut. 2021 Apr 1;274:116539.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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