AHU-377(Sacubitril)

CAT: 0607-B1070-10Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0607-B1070-10Size:10 mg

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Description

Neprilysin inhibitor

CAS Number

149709-62-6

Product Name Alternative

4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid

Sequence

Sacubitril

Field of Research

GPCR G protein Angiotensin Receptor

Purity

0.9865

Form

A colorless oil

Solubility

≥41.1 mg/mL in DMSO; ≥21.45 mg/mL in H2O with ultrasonic; ≥26.85 mg/mL in EtOH with ultrasonic

Smiles

CCOC(=O)C(C)CC(CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O

Molecular Formula

C24H29NO5

Molecular Weight

411.49

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

Chemical Information

Sacubitril

Sacubitril is a member of biphenyls.

CAS Number	149709-62-6
PubChem CID	9811834
IUPAC Name	4-[[(2S,4R)-5-ethoxy-4-methyl-5-oxo-1-(4-phenylphenyl)pentan-2-yl]amino]-4-oxobutanoic acid
Molecular Formula	C24H29NO5
Molecular Weight	411.5
XLogP	3.7
Topological Polar Surface Area	92.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	12
Heavy Atom Count	30
Formal Charge	0
Complexity	550

SMILES

CCOC(=O)[C@H](C)C[C@@H](CC1=CC=C(C=C1)C2=CC=CC=C2)NC(=O)CCC(=O)O

InChI

InChI=1S/C24H29NO5/c1-3-30-24(29)17(2)15-21(25-22(26)13-14-23(27)28)16-18-9-11-20(12-10-18)19-7-5-4-6-8-19/h4-12,17,21H,3,13-16H2,1-2H3,(H,25,26)(H,27,28)/t17-,21+/m1/s1

InChIKey

PYNXFZCZUAOOQC-UTKZUKDTSA-N

Chemical Structure

2D Structure

CAS: 149709-62-6

CID: 9811834

Formula: C24H29NO5

MW: 411.5

Interactive 3D Structure

Loading 3D structure...

View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	411.5
XLogP3	3.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	12
Exact Mass	411.20457303
Monoisotopic Mass	411.20457303
Topological Polar Surface Area	92.7 Å²
Heavy Atom Count	30
Formal Charge	0
Complexity	550
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
B3267-10	AHU-377 hemicalcium salt
B3267-100	AHU-377 hemicalcium salt
B3267-5	AHU-377 hemicalcium salt
B3267-5.1	AHU-377 hemicalcium salt
B3267-50	AHU-377 hemicalcium salt
B3267-S	AHU-377 hemicalcium salt
BA7368-5.1	2R,4R-Sacubitril
SL1055-1	Sacubitril metabolite-13C4
BA7368-5	2R,4R-Sacubitril
BA7369-5	2R,4S-Sacubitril

Alternative Products

Catalog	Name
MBS384159-01	AHU-377 (Sacubitril calcium)
A13682-200	AHU-377 (Sacubitril calcium) 200mg
A13682-100	AHU-377 (Sacubitril calcium) 100mg
A13682-500	AHU-377 (Sacubitril calcium) 500mg
A13682-50	AHU-377 (Sacubitril calcium) 50mg
A13682-10mM-D	AHU-377 (Sacubitril calcium) 10mM * 1mL in DMSO
9520-5	AHU-377
sc-492600	AHU 377
A13682-25	AHU-377 25mg
A13682-10	AHU-377 10mg

AHU-377(Sacubitril)

Chemical Information

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