MK-8745

• Description:

  Aurora A inhibitor,potent and selective

• Product Name Alternative:

  (3-chloro-2-fluorophenyl)(4-((6-(thiazol-2-ylamino)pyridin-2-yl)methyl)piperazin-1-yl)methanone

• Field of Research:

  Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase

• Purity:

  0.9981

• Form:

  A solid

• Solubility:

  ≥21.6 mg/mL in DMSO; insoluble in H2O; ≥2.28 mg/mL in EtOH with gentle warming and ultrasonic

• Smiles:

  ClC1=C(F)C(C(N2CCN(CC3=NC(NC4=NC=CS4)=CC=C3)CC2)=O)=CC=C1

• Molecular Formula:

  C20H19ClFN5OS

• Molecular Weight:

  431.91

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  885325-71-3