D-Cl-amidine (hydrochloride)

D-Cl-amidine (hydrochloride)

• CAS Number: 2985338-61-0
• UNSPSC Description: D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor. D-Cl-amidine is well-torelated with no significant toxicity[1].
• Target Antigen: Apoptosis; Protein Arginine Deiminase
• Type: Reference compound
• Related Pathways: Apoptosis;Epigenetics
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/d-cl-amidine-hydrochloride.html
• Purity: 99.91
• Solubility: DMSO : 32 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 16.67 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: O=C(N[C@@H](C(N)=O)CCCNC(CCl)=N)C1=CC=CC=C1.[H]Cl
• Molecular Weight: 347.24
• References & Citations: [1]Bicker KL, et al. D-amino acid based protein arginine deiminase inhibitors: Synthesis, pharmacokinetics, and in cellulo efficacy. ACS Med Chem Lett. 2012 Oct 26;3(12):1081-1085.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: No Development Reported