ARRY-380

• Description:

  Tyrosine kinase HER2 and p95-HER2 inhibitor

• Product Name Alternative:

  6-[5-[(2-methylsulfonylethylamino)methyl]furan-2-yl]-N-[3-methyl-4-([1,2,4]triazolo[1,5-a]pyridin-7-yloxy)phenyl]quinazolin-4-amine

• Sequence:

  ARRY380; ARRY 380

• Field of Research:

  JAK STAT Signaling EGFR Tyrosine Kinase EGFR

• Purity:

  0.9878

• Form:

  A solid

• Solubility:

  ≥28.5 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

• Smiles:

  CC1=C(C=CC(=C1)NC2=NC=NC3=C2C=C(C=C3)C4=CC=C(O4)CNCCS(=O)(=O)C)OC5=CC6=NC=NN6C=C5

• Molecular Formula:

  C29H27N7O4S

• Molecular Weight:

  569.63

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  937265-83-3