R428

• Description:

  Selective Axl inhibitor

• Product Name Alternative:

  1-(6,7-dihydro-5H-benzo[2,3]cyclohepta[2,4-d]pyridazin-3-yl)-3-N-[(7S)-7-pyrrolidin-1-yl-6,7,8,9-tetrahydro-5H-benzo[7]annulen-3-yl]-1,2,4-triazole-3,5-diamine

• Sequence:

  R-428; R 428; BGB324; Bemcentinib

• Field of Research:

  Tyrosine Kinase Axl

• Purity:

  0.9806

• Form:

  A solid

• Solubility:

  ≥25 mg/mL in DMSO with gentle warming; insoluble in H2O; insoluble in EtOH

• Smiles:

  C1CCN(C1)C2CCC3=C(CC2)C=C(C=C3)NC4=NN(C(=N4)N)C5=NN=C6C(=C5)CCCC7=CC=CC=C76

• Molecular Formula:

  C30H34N8

• Molecular Weight:

  506.64

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1037624-75-1