Dacomitinib (PF299804, PF299)

• Description:

  HER inhibitor

• Product Name Alternative:

  (E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-piperidin-1-ylbut-2-enamide

• Sequence:

  PF-00299804; PF-299804; PF 299804; PF 00299804

• Field of Research:

  JAK STAT Signaling EGFR Tyrosine Kinase EGFR

• Purity:

  0.9987

• Form:

  A solid

• Solubility:

  ≥23.5 mg/mL in DMSO; insoluble in H2O; ≥8.76 mg/mL in EtOH with gentle warming and ultrasonic

• Smiles:

  COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)NC(=O)C=CCN4CCCCC4

• Molecular Formula:

  C24H25ClFN5O2

• Molecular Weight:

  469.94

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1110813-31-4