PF-562271

• Description:

  ATP-competitive FAK inhibitor, reversible

• Product Name Alternative:

  N-methyl-N-[3-[[[2-[(2-oxo-1,3-dihydroindol-5-yl)amino]-5-(trifluoromethyl)pyrimidin-4-yl]amino]methyl]pyridin-2-yl]methanesulfonamide

• Sequence:

  PF562271;PF 562271

• Field of Research:

  Tyrosine Kinase FAK TGF-β Smad Signaling Pyk2 Tyrosine Kinase Pyk2

• Purity:

  0.9785

• Form:

  A solid

• Solubility:

  ≥25.35 mg/mL in DMSO; insoluble in H2O; ≥2.25 mg/mL in EtOH with gentle warming and ultrasonic

• Smiles:

  CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C

• Molecular Formula:

  C21H20F3N7O3S

• Molecular Weight:

  507.49

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  717907-75-0