Regorafenib

• Description:

  Inhibitor of VEGFR/PDGFR/FGFR/mutant kit/RET/Raf-1

• Product Name Alternative:

  4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)-3-fluorophenoxy)-N-methylpicolinamide

• Sequence:

  BAY 73-4506

• Field of Research:

  Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase PDGFR Tyrosine Kinase VEGFR

• Purity:

  0.9946

• Form:

  A solid

• Solubility:

  ≥25.04 mg/mL in DMSO; insoluble in H2O; ≥6.25 mg/mL in EtOH with ultrasonic

• Smiles:

  O=C(NC)C1=CC(OC2=CC=C(NC(NC3=CC=C(Cl)C(C(F)(F)F)=C3)=O)C(F)=C2)=CC=N1

• Molecular Formula:

  C21H15ClF4N4O3

• Molecular Weight:

  482.82

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Desiccate at -20°C.

• CAS Number:

  755037-03-7