Nilotinib(AMN-107)

Nilotinib(AMN-107)

• Description: Bcr-Abl kinase inhibitor,selective
• Product Name Alternative: 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide
• CAS Number: 641571-10-0
• Sequence: AMN-107; Tasigna; AMN107
• Field of Research: TGF-β Smad Signaling Bcr-Abl Tyrosine Kinase Bcr-Abl
• Purity: 0.9985
• Form: A solid
• Solubility: ≥26.5 mg/mL in DMSO; insoluble in H2O; ≥5 mg/mL in EtOH with gentle warming and ultrasonic
• Smiles: CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5
• Molecular Formula: C28H22F3N7O
• Molecular Weight: 529.53
• Shipping Conditions: Blue ice
• Storage Conditions: Store at -20°C.