Nilotinib(AMN-107)

• Description:

  Bcr-Abl kinase inhibitor,selective

• Product Name Alternative:

  4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide

• Sequence:

  AMN-107; Tasigna; AMN107

• Field of Research:

  TGF-β Smad Signaling Bcr-Abl Tyrosine Kinase Bcr-Abl

• Purity:

  0.9985

• Form:

  A solid

• Solubility:

  ≥26.5 mg/mL in DMSO; insoluble in H2O; ≥5 mg/mL in EtOH with gentle warming and ultrasonic

• Smiles:

  CC1=C(C=C(C=C1)C(=O)NC2=CC(=CC(=C2)N3C=C(N=C3)C)C(F)(F)F)NC4=NC=CC(=N4)C5=CN=CC=C5

• Molecular Formula:

  C28H22F3N7O

• Molecular Weight:

  529.53

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  641571-10-0