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Staurosporine

CAT: 0607-A8192-5Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0607-A8192-5Size:5 mg
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Description
Protein kinase inhibitor,potent and cell permeable
CAS Number
62996-74-1
Product Name Alternative
(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14(5H)-one
Field of Research
Tyrosine Kinase Broad Spectrum Protein Kinase Inhibitor TGF-β Smad Signaling PKC
Purity
0.9967
Form
A solid
Solubility
insoluble in H2O; insoluble in EtOH; ≥11.66 mg/mL in DMSO
Smiles
O=C(NC1)C2=C1C3=C(C4=C2C5=C(C=CC=C5)N4[C@H]6C[C@@H](NC)[C@@H](OC)[C@]7(C)O6)N7C8=CC=CC=C83
Molecular Formula
C28H26N4O3
Molecular Weight
466.53
Shipping Conditions
Blue ice
Storage Conditions
Store at -20°C.

Chemical Information

Staurosporine

Staurosporine is an indolocarbazole alkaloid and an organic heterooctacyclic compound. It has a role as a geroprotector, an EC 2.7.11.13 (protein kinase C) inhibitor, an apoptosis inducer and a bacterial metabolite. It is a conjugate base of a staurosporinium.

CAS Number62996-74-1
PubChem CID44259
IUPAC Name(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
Molecular FormulaC28H26N4O3
Molecular Weight466.5
XLogP3.2
Topological Polar Surface Area69.5
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Heavy Atom Count35
Formal Charge0
Complexity901
SMILES
C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC
InChI
InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
InChIKey
HKSZLNNOFSGOKW-FYTWVXJKSA-N
Chemical Structure
2D Structure
2D structure of Staurosporine
CAS: 62996-74-1
CID: 44259
Formula: C28H26N4O3
MW: 466.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight466.5
XLogP33.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count2
Exact Mass466.20049070
Monoisotopic Mass466.20049070
Topological Polar Surface Area69.5 Ų
Heavy Atom Count35
Formal Charge0
Complexity901
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Alternative Products

CatalogName
S070-25MGStaurosporine

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