Staurosporine

CAT: 0607-A8192-5.1Size: 10 mM (in 1mL DMSO)Dry Ice: NoHazardous: No

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CAT#:0607-A8192-5.1Size:10 mM (in 1mL DMSO)

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Description

Protein kinase inhibitor,potent and cell permeable

CAS Number

62996-74-1

Product Name Alternative

(5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-17-oxa-4b,9a,15-triaza-5,9-methanodibenzo[b,h]cyclonona[jkl]cyclopenta[e]-as-indacen-14(5H)-one

Field of Research

Tyrosine Kinase Broad Spectrum Protein Kinase Inhibitor TGF-β Smad Signaling PKC

Purity

0.9967

Form

A solid

Solubility

insoluble in H2O; insoluble in EtOH; ≥11.66 mg/mL in DMSO

Smiles

O=C(NC1)C2=C1C3=C(C4=C2C5=C(C=CC=C5)N4[C@H]6C[C@@H](NC)[C@@H](OC)[C@]7(C)O6)N7C8=CC=CC=C83

Molecular Formula

C28H26N4O3

Molecular Weight

466.53

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

Chemical Information

Staurosporine

Staurosporine is an indolocarbazole alkaloid and an organic heterooctacyclic compound. It has a role as a geroprotector, an EC 2.7.11.13 (protein kinase C) inhibitor, an apoptosis inducer and a bacterial metabolite. It is a conjugate base of a staurosporinium.

CAS Number	62996-74-1
PubChem CID	44259
IUPAC Name	(2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-16-one
Molecular Formula	C28H26N4O3
Molecular Weight	466.5
XLogP	3.2
Topological Polar Surface Area	69.5
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Heavy Atom Count	35
Formal Charge	0
Complexity	901

SMILES

C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)NC)OC

InChI

InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1

InChIKey

HKSZLNNOFSGOKW-FYTWVXJKSA-N

Chemical Structure

2D Structure

CAS: 62996-74-1

CID: 44259

Formula: C28H26N4O3

MW: 466.5

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	466.5
XLogP3	3.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	466.20049070
Monoisotopic Mass	466.20049070
Topological Polar Surface Area	69.5 Å²
Heavy Atom Count	35
Formal Charge	0
Complexity	901
Isotope Atom Count	0
Defined Atom Stereocenter Count	4
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Alternative Products

Catalog	Name
1048-01	Staurosporine

Staurosporine

Chemical Information

Alternative Products

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