Danusertib (PHA-739358)

• Description:

  Pan-aurora kinase inhibitor

• Product Name Alternative:

  N-[5-[(2R)-2-methoxy-2-phenylacetyl]-4,6-dihydro-1H-pyrrolo[3,4-c]pyrazol-3-yl]-4-(4-methylpiperazin-1-yl)benzamide

• Sequence:

  5-Amido-pyrrolopyrazole 9d

• Field of Research:

  Cell Cycle Checkpoint Aurora Kinase Chromatin Epigenetics Aurora Kinase Apoptosis c-RET Tyrosine Kinase c-RET Tyrosine Kinase FGFR

• Purity:

  0.9939

• Form:

  A solid

• Solubility:

  ≥23.75 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O

• Smiles:

  CN1CCN(CC1)C2=CC=C(C=C2)C(=O)NC3=NNC4=C3CN(C4)C(=O)C(C5=CC=CC=C5)OC

• Molecular Formula:

  C26H30N6O3

• Molecular Weight:

  474.55

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  827318-97-8