Trametinib DMSO solvate

CAT: 0607-A3887-50Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0607-A3887-50Size:50 mg

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Description

Allosteric MEK1/MEK2 kinase inhibitor

CAS Number

1187431-43-1

Product Name Alternative

N-[3-[3-cyclopropyl-5-(2-fluoro-4-iodoanilino)-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide;methylsulfinylmethane

Sequence

GSK-1120212 DMSO solvate;Trametinib;JTP-74057;GSK-1120212;GSK1120212;GSK 1120212;JTP 74057;JTP74057

Field of Research

MAPK Signaling MEK1 2

Purity

0.9864

Form

A solid

Solubility

insoluble in EtOH; insoluble in H2O; ≥11.2 mg/mL in DMSO with gentle warming and ultrasonic

Smiles

CC1=C2C(=C(N(C1=O)C)NC3=C(C=C(C=C3)I)F)C(=O)N(C(=O)N2C4=CC(=CC=C4)NC(=O)C)C5CC5.CS(=O)C

Molecular Formula

C28H29FIN5O5S

Molecular Weight

693.53

Shipping Conditions

Blue ice

Storage Conditions

Store at -20°C.

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