GDC-0068 (RG7440)

• Description:

  Pan-AKT inhibitor,highly selective

• Product Name Alternative:

  (2S)-2-(4-chlorophenyl)-1-[4-[(5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl]piperazin-1-yl]-3-(propan-2-ylamino)propan-1-one

• Sequence:

  GDC0068,RG7440,CS0975

• Field of Research:

  PI3K Akt mTOR Signaling Akt

• Purity:

  0.9906

• Form:

  A solid

• Solubility:

  ≥22.9 mg/mL in DMSO; insoluble in H2O; ≥28.35 mg/mL in EtOH

• Smiles:

  CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O

• Molecular Formula:

  C24H32ClN5O2

• Molecular Weight:

  458

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Desiccate at -20°C.

• CAS Number:

  1001264-89-6