WZ8040

• Description:

  EGFR T790M inhibitor,irreversible amd potent

• Product Name Alternative:

  N-[3-[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]oxyphenyl]prop-2-enamide

• Field of Research:

  JAK STAT Signaling EGFR Tyrosine Kinase EGFR

• Purity:

  0.9836

• Form:

  A solid

• Solubility:

  ≥24.05 mg/mL in DMSO; insoluble in H2O; ≥2.61 mg/mL in EtOH with gentle warming and ultrasonic

• Smiles:

  CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)SC4=CC=CC(=C4)NC(=O)C=C)Cl

• Molecular Formula:

  C24H25ClN6OS

• Molecular Weight:

  481.01

• Shipping Conditions:

  Blue ice

• Storage Conditions:

  Store at -20°C.

• CAS Number:

  1214265-57-2