(2R,4R)-Fmoc-D-Pro(4-N3)-OH

(2R,4R)-Fmoc-D-Pro(4-N3)-OH

• CAS Number: 1378847-51-8
• UNSPSC Description: (2R,4R)-Fmoc-D-Pro(4-N3)-OH (cis-4-Azido-N-Fmoc-D-proline) is a click chemistry reagent containing an azide group[1]. It contains an azide group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. It can also undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups.
• Target Antigen: ADC Linker
• Type: Reference compound
• Related Pathways: Antibody-drug Conjugate/ADC Related
• Applications: Cancer-programmed cell death
• Field of Research: Others
• Assay Protocol: https://www.medchemexpress.com/2r-4r-fmoc-d-pro-4-n3-oh.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1[C@H](C[C@H](C1)N=[N+]=[N-])C(O)=O)OCC2C3=CC=CC=C3C4=CC=CC=C42
• Molecular Weight: 378.38
• References & Citations: [1]Rashad AA, et al. Macrocyclic Envelope Glycoprotein Antagonists that Irreversibly Inactivate HIV-1 before Host Cell Encounter. J Med Chem. 2015 Sep 24;58(18):7603-8.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported