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CpG ODN 10101 (sodium)

CAT: 0804-HY-150217A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150217A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CpG ODN 10101 sodium, a synthetic oligodeoxynucleotide (ODN), is a toll-like receptor 9 (TLR9) agonist. CpG ODN 10101 sodium is a potent inducer of cytokine/chemokine expression ex vivo when used in combination with HH2 (VQLRIRVAVIRA-NH2) . CpG ODN 10101 sodium induces IFN- secretion from dendritic cells (DCs) and stimulates B-cells.CpG ODN 10101 sodium has antiviral and immunomodulatory properties that can influence chronic infection with HCV[1][2].
Product Name Alternative
ODN 10101 (sodium)
UNSPSC
12352208
Target
Toll-like Receptor (TLR)
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cpg-odn-10101-sodium.html
Purity
98.84
Solubility
10 mM in H2O
Smiles
[CpGODN10101(sodium)]
Molecular Weight
7185.00
References & Citations
[1]John G McHutchison, et al. Phase 1B, randomized, double-blind, dose-escalation trial of CPG 10101 in patients with chronic hepatitis C virus. Hepatology. 2007 Nov;46 (5) :1341-9.|[2]Jason Kindrachuk, et al. A novel vaccine adjuvant comprised of a synthetic innate defence regulator peptide and CpG oligonucleotide links innate and adaptive immunity. Vaccine. 2009 Jul 23;27 (34) :4662-71.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported

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