8-Iso-15-keto prostaglandin F2β

8-Iso-15-keto prostaglandin F2β

• CAS Number: 1621482-36-7
• UNSPSC Description: 8-ISo-15-keto prostaglandin F2β is a potential metabolite of 8-Iso PGF2β via the 15-hydroxy-PG dehydrogenase pathway. 8-iso PGF2β constricts pulmonary veins in dogs and pigs[1][2].
• Target Antigen: Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology
• Assay Protocol: https://www.medchemexpress.com/8-iso-15-keto-prostaglandin-f2β.html
• Solubility: 10 mM in DMSO
• Smiles: OC(CCC/C=C\C[C@H]1[C@H]([C@@H](C[C@H]1O)O)/C=C/C(CCCCC)=O)=O
• Molecular Weight: 352.47
• References & Citations: [1]Janssen LJ, et al. Vasoconstrictor actions of isoprostanes via tyrosine kinase and Rho kinase in human and canine pulmonary vascular smooth muscles. Br J Pharmacol. 2001 Jan;132(1):127-34.|[2]Janssen LJ, et al. Involvement of TP and EP3 receptors in vasoconstrictor responses to isoprostanes in pulmonary vasculature. J Pharmacol Exp Ther. 2002 Jun;301(3):1060-6.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported