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Bemarituzumab

CAT: 0804-HY-P99010-01Size: 1 mgDry Ice: YesHazardous: No
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CAT#:0804-HY-P99010-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Bemarituzumab is a humanized IgG1 monoclonal antibody against FGFR2b (a FGF receptor) . Bemarituzumab blocks fibroblast growth factors from binding and activating FGFR2b. Bemarituzumab has antitumor activity against gastric and breast cancer[1][2].
CAS Number
1952272-74-0
UNSPSC
12352203
Target
FGFR
Type
Inhibitory Antibodies
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bemarituzumab.html
Purity
99.82
Solubility
H2O
Smiles
[Bemarituzumab]
Molecular Weight
(143.86 kDa)
References & Citations
[1]Daniel Vt Catenacci, et al. Bemarituzumab with modified FOLFOX6 for advanced FGFR2-positive gastroesophageal cancer: FIGHT Phase III study design. Future Oncol. 2019 Jun;15 (18) :2073-2082.|[2]Xiang H, et al. Preclinical characterization of bemarituzumab, an anti-FGFR2b antibody for the treatment of cancer. MAbs. 2021 Jan-Dec;13 (1) :1981202.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3

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