Products for Research Use Only
RegisterLogin

EPZ030456

CAT: 0804-HY-122223Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-122223Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
EPZ030456 is a potent and selective SMYD3 inhibitor with an IC50 of 48 nM. EPZ030456 can be used for cancer research[1].
CAS Number
1808011-23-5
UNSPSC
12352005
Target
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/epz030456.html
Smiles
O=S(N1[C@]2([H])C[C@H](C[C@@]1([H])CC2)NC(C3=C(Cl)C=C(NC(C4)=O)C4=C3)=O)(N5CCC(CC5)NCC6=CC=CC=C6)=O
Molecular Formula
C28H34ClN5O4S
Molecular Weight
572.12
References & Citations
[1]Lorna H Mitchell, et al. Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor. ACS Med Chem Lett. 2015 Aug 27;7 (2) :134-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Popular Products