(-) -Isocorypalmine

CAT: 0804-HY-N0927-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N0927-01Size:1 mg
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Description
(-) -Isocorypalmine (Tetrahydrocolumbamine), isolated from the crude base fraction of Corydalis chaerophylla, is a dopamine receptor ligand[1]. Recombinant CYP719A21 displays strict substrate specificity and high affinity (Km=4.63 ± 0.71 μM) for (-) -Isocorypalmine[2].
CAS Number
[483-34-1]
Product Name Alternative
Tetrahydrocolumbamine; (S) -Tetrahydrocolumbamine
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Dopamine Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/_-_-Isocorypalmine.html
Purity
99.67
Solubility
DMSO : ≥ 6.67 mg/mL
Smiles
OC(C=C1[C@@]2([H])N3CC4=C(C=CC(OC)=C4OC)C2)=C(C=C1CC3)OC
Molecular Formula
C20H23NO4
Molecular Weight
341.40
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Shen XL, et al. Isolation and identification of tetrahydrocolumbamine as a dopamine receptor ligand from Polygala tenuifolia Willd. Yao Xue Xue Bao. 1994;29 (12) :887-890.|[2]Dang TT, et al. Cloning and characterization of canadine synthase involved in noscapine biosynthesis in opium poppy. FEBS Lett. 2014;588 (1) :198-204.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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