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Oxyresveratrol

CAT: 0804-HY-N1430-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-N1430-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxyresveratrol (trans-Oxyresveratrol) is a potent naturally occurring antioxidant and free radical scavenger (IC50 of 28.9 μM against DPPH free radicals) . Oxyresveratrol is potent and noncompetitive tyrosinase inhibitor with an IC50 value of 1.2 μM for mushroom tyrosinase. Oxyresveratrol is effective against HSV-1, HSV-2 and varicella-zoster virus, and has neuroprotective effects[1][2][3][4].
CAS Number
29700-22-9
Product Name Alternative
Trans-Oxyresveratrol
UNSPSC
12352005
Hazard Statement
H319
Target
Autophagy; HSV; Tyrosinase
Type
Natural Products
Related Pathways
Anti-infection; Autophagy; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Oxyresveratrol.html
Purity
99.73
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=CC=C(/C=C/C2=CC(O)=CC(O)=C2)C(O)=C1
Molecular Formula
C14H12O4
Molecular Weight
244.24
Precautions
H319
References & Citations
[1]Lorenz. et al. Oxyresveratrol and resveratrol are potent antioxidants and free radical scavengers: Effect on nitrosative and oxidative stress derived from microglial cells. Nitric Oxide 9 (2) 64-76 (2003) .|[2]Kim, Y.M., Yun, J., Lee, C., et al. Oxyresveratrol and hydroxystilbene compounds. Inhbitory effect on tyrosinase and mechanism of action. J Biol Chem277 (18) 16340-16344 (2002) .|[3]Shaida A Andrabi et al. Oxyresveratrol (trans-2,3′,4,5′-tetrahydroxystilbene) is neuroprotective and inhibits the apoptotic cell death in transient cerebral ischemia. Brain Res, 2004 Aug 13, 1017 (1-2) :98-107.|[4]Vimolmas Lipipun, et al. Topical cream-based oxyresveratrol in the treatment of cutaneous HSV-1 infection in mice. Antiviral Res. 2011 Aug;91 (2) :154-60.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
HSV-1; HSV-2