Aplindore

• Description :

  Aplindore (DAB-452) is a potent agonist of the dopamine D2 receptor, with the pKi of 9.1. Aplindore plays an important role in Parkinson's disease research[1].

• Product Name Alternative :

  DAB-452

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Dopamine Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/aplindore.html

• Purity :

  98.44

• Smiles :

  O=C(C1)NC2=C1C(O[C@H]3CNCC4=CC=CC=C4)=C(OC3)C=C2

• Molecular Formula :

  C18H18N2O3

• Molecular Weight :

  310.35

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Julia N Heinrich, et al. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist. Eur J Pharmacol. 2006 Dec 15;552 (1-3) :36-45.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  D2 Receptor

• CAS Number :

  [189681-70-7]