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Aplindore

CAT: 0804-HY-W966282-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W966282-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Aplindore (DAB-452) is a potent agonist of the dopamine D2 receptor, with the pKi of 9.1. Aplindore plays an important role in Parkinson's disease research[1].
CAS Number
189681-70-7
Product Name Alternative
DAB-452
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/aplindore.html
Purity
98.44
Smiles
O=C(C1)NC2=C1C(O[C@H]3CNCC4=CC=CC=C4)=C(OC3)C=C2
Molecular Formula
C18H18N2O3
Molecular Weight
310.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Julia N Heinrich, et al. Aplindore (DAB-452), a high affinity selective dopamine D2 receptor partial agonist. Eur J Pharmacol. 2006 Dec 15;552 (1-3) :36-45.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
D2 Receptor

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